ОПТИМИЗАЦИЯ УСЛОВИЙ ЛАБОРАТОРНОГО ПОЛУЧЕНИЯ АЦЕТАТА НАТРИЯ ВЫСОКОЙ ЧИСТОТЫ

Authors

  • О.М. Сейтназарова

    Karakalpak State University image/svg+xml

  • Ш.А. Кулдашева

    Termez State Pedagogical Institute image/svg+xml

  • А.Б. Абдикамалова

    Институт общей и неорганической химии Академии наук Республики Узбекистан

  • Ж.Т. Юсупов

    Karakalpak State University image/svg+xml

  • Г.Э. Кувватова

    Karakalpak State University image/svg+xml

Keywords: sodium acetate, calcium carbonate, mini-technology, laboratory synthesis, purity, pH, temperature

Abstract

The article presents the development of a mini-technology for obtaining high-purity sodium acetate based on the interaction of calcium carbonate (CC) and acetic acid (AC) with subsequent replacement of calcium with sodium carbonate. The influence of process parameters (pH, temperature, reagent ratio, mixing rate, and crystallization mode) on product yield and purity was investigated. It was established that the optimal conditions (pH1 = 6.8-7.2; pH2 = 7.5-7.9; melting point 40-45 °C; crystallization point 10-15 °C) provide 82-83% of theoretical yield and 99.5-99.6% sodium acetate purity. The calcium content in the final product does not exceed 0.01%, heavy metals - 0.002%. The developed methodology is distinguished by its ease of implementation, the use of available reagents, and can be implemented in university laboratories and research institutes.

References

1. Dmitri Soloviev, Claire Tamburella. Captive solvent acetate synthesis in GMP conditions. // Applied Radiation and Isotopes, Volume 64, Issue 9, 2006. – P. 995-1000.

2. Hua W., Zhang X., Muthoka MJ., Han X. Preparation and Performance Analysis of Modified Sodium Acetate Trihydrate. // Materials (Basel). 2018 Jun 15;11(6):1016.

3. Rajabzadeh M. Determination of sodium acetate concentration by the method of standard additions. // Journal of Chemical Education. 2012. Vol. 89, № 9. – P. 1154-1156.

4. Патент CN101139280A (Китай). Sodium acetate anhydrous and preparation method and usage thereof / Song Guilan, Deng Yong; заявитель и патентообладатель Hubei Duorui Pharmaceutical Co., Ltd. – Заявка № CN2007101574446A от 11.10.2007; опубл. 12.03.2008.

5. Патент CN103833543A (Китай). Preparation method of sodium acetate / Qin Hanchao, Su Xuesong, Chen Shu, Li Gang, Lin Licheng; заявитель и патентообладатель Tianjin Kermel Chemical Reagent Co., Ltd. – Заявка № CN201210473961.5A от 21.11.2012; опубл. 04.06.2014.

6. https://en.wikipedia.org/wiki/Sodium_acetate#:~:text=For%20laboratory%20use%2C%20sodium%20acetate,the%20Niacet%20Process%20is%20used.

7. Патент CN102351679A (Китай). Method for producing crystalline sodium acetate with one-step method / Li Jianzhong, Li Huailai; заявитель и патентообладатель Dongying Jinming Industrial Co., Ltd. Заявка № CN2011103032886A от 10.10.2011; опубл. 15.02.2012.